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IN "THE ANTIDOTE," Barry Werth draws upon unprecedented inside
reporting spanning more than two decades to provide a
groundbreaking closeup of the upstart pharmaceutical company Vertex
and the ferocious but indispensable world of Big Pharma that it
inhabits.
In 1989, the charismatic Joshua Boger left Merck, then America's
most admired business, to found a drug company that would challenge
industry giants and transform health care. Werth described the
company's tumultuous early days during the AIDS crisis in "The
Billion-Dollar Molecule," a celebrated classic of science and
business journalism. Now he returns to tell a riveting story of
Vertex's bold endurance and eventual success.
The $325 billion-a-year pharmaceutical business is America's
toughest and one of its most profitable. It's riskier and more
rigorous at just about every stage than any other business, from
the towering biological uncertainties inherent in its mission to
treat disease; to the 30-to-1 failure rate in bringing out a
successful medicine even after a molecule clears all the hurdles to
get to human testing; to the multibillion-dollar cost of ramping up
a successful product; to operating in the world's most regulated
industry, matched only by nuclear power.
Werth captures the full scope of Vertex's twentyfive- year drive to
deliver breakthrough medicines. At a time when America struggles to
maintain its innovative edge, "The Antidote" is a powerful inside
look at one of the most intriguing and important business stories
of recent decades.
Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing -- atom by atom -- both a new life-saving immunosuppressant drug, and a drug to combat the virus that causes AIDS. You will be hooked from start to finish, as you go from the labs, where obsessive, fiercely competitive scientists struggle for a breakthrough, to Wall Street, where the wheeling and dealing takes on a life of its own, as Boger courts investors and finally decides to take Vertex public. Here is a fascinating no-holds-barred account of the business of science, which includes an updated epilogue about the most recent developments in the quest for a drug to cure AIDS.
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Damages (Paperback)
Barry Werth
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R738
R655
Discovery Miles 6 550
Save R83 (11%)
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Ships in 10 - 15 working days
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DAMAGES is the riveting true story of one family's legal struggles
in the world of medicine. At the urging of a friend, the Sabias
filed a medical malpractice lawsuit against Dr. Humes and Norwalk
Hospital. Barry Werth takes us through the seven-year lawsuit,
allowing us to see the legal strategy plotted by the Sabias'
attorneys, Connecticut's premier medical malpractice law firm.
In "31 Days," acclaimed historian Barry Werth takes readers inside
the White House during the tumultuous days of August 1974,
following Richard Nixon's resignation and the swearing-in of
America's "accidental president," Gerald Ford.
The Watergate scandal had torn the country apart. In a dramatic,
day-by-day account of the new administration's inner workings,
Werth shows how Ford, caught between political expedience, the
country's demands for justice, and his own moral compass, struggled
valiantly to restore the nation's tarnished faith in its
leadership. With deft and refreshing analysis Werth illuminates how
this unprecedented political upheaval produced new fissures and
battle lines, as well as new opportunities for political
advancement for ambitious young men such as Donald Rumsfeld, who
had been Nixon's ambassador to NATO, and Dick Cheney, already
coolly efficient as Rumsfeld's former deputy. A superbly crafted
presidential history with all of the twists and turns of a
thriller, "31 Days" sheds new light on the key players and
political dilemmas that reverberate in today's headlines.
During his thirty-seven years at Smith College, Newton Arvin published groundbreaking studies of Hawthorne, Whitman, Melville, and Longfellow that stand today as models of scholarship and psychological acuity. He cultivated friendships with the likes of Edmund Wilson and Lillian Hellman and became mentor to Truman Capote. A social radical and closeted homosexual, the circumspect Arvin nevertheless survived McCarthyism. But in September 1960 his apartment was raided, and his cache of beefcake erotica was confiscated, plunging him into confusion and despair and provoking his panicked betrayal of several friends.
An utterly absorbing chronicle, The Scarlet Professor deftly captures the essence of a conflicted man and offers a provocative and unsettling look at American moral fanaticism.
In "Banquet at Delmonico's," Barry Werth draws readers inside
the circle of intellectuals, scientists, politicians, businessmen,
and clergymen who brought Charles Darwin's controversial ideas to
post-Civil-War America. Each chapter is dedicated to a crucial
intellectual encounter, culminating with an exclusive farewell
dinner held in English philosopher Herbert Spencer's honor at the
venerable New York restaurant Delmonico's in 1882. In this
thought-provoking and nuanced account, Werth firmly situates social
Darwinism in the context of the Gilded Age. "Banquet at Delmonico's
"is social history at its finest.
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